If the in-vitro fertilization method does not result in a favorable pregnancy due to poor quality of embryos, it is worth referring to more experienced reproductive specialists. Our highly qualified doctors of our center, who are familiar with all modern IVF methods, can help you in such a situation.
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Doctors of use the most effective reproductive techniques in their work. Hatching procedure is highly effective. Its essence consists of performing microcutting in the embryo membrane. This method is chosen when several in vitro fertilization attempts have failed.
Specialists also perform other procedures to determine the cause of in vitro fertilization failure:
- In the case of an insufficient ovarian response. It is important to find out to what extent it does not correspond to the norm, and what should be done to improve it in the future. If the response was weak/excessive or triggered SVF, it is worth considering changing the protocol, using other hormones, or reviewing their dosage.
- When fertilization rates are low and oocyte quality is not high enough. If after an unsuccessful IVF attempt the fertilization rate was low, the next time the method of ICSI may be helpful. If the quality of oocytes is unsatisfactory, donor material can be used, or IVF can be performed in a natural cycle.
- If the structure and thickness of the endometrium do not correspond to normal values. If there are any abnormalities, hysteroscopy is considered before attempting IVF again. If the endometrium is too thin, Doppler mapping of the uterine vessels, pipelle-biopsy, uterine cavity culture, and subsequent correction of detected defects are indicated.
- In case changes in the fallopian tubes are detected. When preparing for the IVF program, it is very important to detect the presence of hydrosalpinx in time, requiring the removal of abnormal tubes during laparoscopy. If this problem occurs, the possibility of cryopreservation of the obtained embryos and their subsequent transfer in a cryocycler is also considered.
- If the state of the partner’s sperm at the time of the puncture is not satisfactory. Despite choosing the most suitable sperm for fertilization in the ICSI procedure, in some cases, the embryologist is forced to use the best of the worst sperm, which becomes one of the reasons for the unsuccessful procedure.
In the case of IVF failure, the patient should maintain close cooperation with the attending physician. Only an experienced specialist will be able to carefully analyze the situation, determine the cause of the problem, and select ways to solve it effectively.