By now you may have heard about the various benefits that CDP Choline supplements provide, but still, you might want to know more about the best Citicoline supplement.

CDP Choline means Cytidine Diphosphate Choline but more commonly known as Citicoline. This substance is a nootropic, a brain enhancing supplement, and is an improved version of Choline. Choline is a nutrient that has been associated with better brain functioning, memory, and even a higher IQ.

Choline is not a component that has been lab tested; it exists naturally and is produced within the human body in the most active form. As a source of Choline, CDP Choline is able to raise the levels of acetylcholine in the brain, this is important because the supplement acts as an essential neurotransmitter for synaptic plasticity and learning.

This supplement is also utilized during the synthesis of cell membranes and it’s linked to higher levels of other neurotransmitters and brain chemicals.

How does CDP Citicoline work?

In order to purchase the best citicoline supplement, firstly you will need to know how they work. When the CDP compound is given independently, the cytidine and choline are provided by CDP-choline. After these compounds reach the brain, they play the role of substrates so that they can synthesize with phosphatidylcholine which is a major component of neuronal membrane. Citicoline is also helpful in the process of enhancement of synthesis of brain acetylcholine.

Short term and long term effects & side effects:

If one was to talk about the effects of the supplements, when you buy the best citicoline supplement, they are known to enhance cognitive skills and improve the performance of the brain. This supplement not only protects brain cells but also promotes the growth of healthy neurons. The endogenous plasticity of the brain is further improved and reconstructed with the introduction of citicoline.

Many people can tolerate the citicoline component in their body up to a certain amount in a good manner, because of its low toxicity level the compound dissolves in the body quite easily and doesn’t demonstrate any kind of danger to the liver. However, there are chances that some people might notice slight gastrointestinal problems if they take the drug for a long time. If the compound is paired with racetams, the user may suffer from mild side effects. In very rare cases it’s been said that patients suffer from insomnia and rashes, but this only happens when the compound is taken in high doses. On the whole, Citicoline has no life-threatening side effects.

CDP Choline dosage:

The recommended dosage for when you purchase the best citicoline supplement is normally 500 to 2000 mg. Since CDP Choline is soluble in water, it should be taken twice a day; once in a drink with water during lunch and once at night along with dinner. The dose range can vary from person to person due to age, health and other various reasons.

Does CDP choline work?

The compound CDP IS hydrolyzed into two separate compounds that are Choline and cytidine within the intestines. After the compound crosses the blood-brain barrier it is absorbed as CDP Choline where it’s used and absorbed through the Acetylcholine receptors which are responsible for thought and memory creation. The benefit of this nootropic is that it’s caused by the conservation of Cardiolipin and Sphingomyelin. Citicoline also assists in enhancing the signaling of many neuro-receptors like acetylcholine, norepinephrine, and dopamine. There are many variables that are yet to determine the improvement of cognitive abilities. This can make it hard to determine just how effective CDP Choline can be for one person.


Hopefully, the above article has helped in your knowledge about CDP Choline Supplements and will help you make the best decision when you have to purchase the best citicoline supplement. If you have any more information to share or suggestion to provide, you can leave it in the comment section below.